AGGREGATION of platelets in the presence of adenosine diphosphate (ADP) appears to be important in hæmostasis and in the genesis of platelet thrombosis. There is evidence that this reaction is common ...

A recently described hemorrhagic disorder characterized by defective platelet aggregation induced by collagen and epinephrine appears to be caused, in part, by the same abnormality induced by aspirin ...

OBJECTIVE: To investigate the role of phospholipase C (PLC), phospholipase A 2 (PLA 2), calcium, and protein kinase C (PKC) in mediating leptin-enhanced aggregation of human platelets. DESIGN: In ...

Proteolytic degradation products of fibrinogen, produced as a result of excessive fibrinolysis, have been demonstrated in the blood of cirrhotic patients. 7,8 Such degradation products, when formed in ...

The first study to examine the effects of whole-chocolate consumption on ex vivo platelet function has shown that dark chocolate acutely reduces collagen-stimulated platelet aggregation and reduces ...

In a recent study published in the IUBMB journal, researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ...

Targeting Na+/K+ ATPase alpha 1 (ATP1A1) subunit proteins could help identify novel therapies for addressing blood clots and thrombosis, according to a new study by Marshall University researchers.

A significant proportion of patients with chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) experience bleeding when taking ibrutinib—a recent study probes why. A new study of patients ...

This medication is a platelet aggregation inhibitor, prescribed for thrombotic cardiovascular (CV) events (life-threatening problems with the heart and blood vessels), in patients who had heart ...