Adolore BioTherapeutics Announces FDA Orphan Drug Designation for its Kv7-activating rdHSV-CA8* Therapy in the Treatment of Erythromelalgia

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...

Exploring mutations that spontaneously switch on a key brain cell receptor

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
MedPage Today

Novel Drug for HER2-Mutant Lung Cancer Wins FDA Approval

The FDA on Friday granted accelerated approval to zongertinib (Hernexeos) for non-squamous non-small cell lung cancer (NSCLC) patients harboring HER2 tyrosine kinase domain (TKD) activating mutations.
Mirage News

Mutations Trigger Key Brain Cell Receptor Activation

Many people are familiar with histamine, a biological molecule, that serves as a key driver of allergic reactions and other immune responses. However ...

Ribosomal engineering creates 'super-probiotic' bacteria with enhanced immune activation

Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
ascopubs.org

Clinical Activity of Mitogen-Activated Protein Kinase Inhibitors in Patients With MAP2K1 (MEK1)-Mutated Metastatic Cancers

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

Scientists report new immune insights and targets into LRRK2 mutations in Parkinson's disease

Parkinson's disease (PD) is a debilitating and progressive neurodegenerative disorder caused by the loss of ...