Early detection of safety liabilities of new therapies is a critical biopharmaceutical challenge. Addressing this challenge could significantly advance drug discovery. Advanced human cell models, ...

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell behavior, limiting ...

New confocal fluorescence imaging minimizes photobleaching and phototoxicity effects, capturing clear images of live 3D culture Industry-leading throughput enables real-time analysis of up to six ...

Peripheral neuropathy (PN) is a dose-limiting side effect of chemotherapeutic and antibody drug conjugate (ADC) treatment which significantly impacts patients’ quality of life. Despite a high clinical ...

CompagOS has produced biologically reproducible Bon3OID™ bone models using 3D bioprinting. Find out more in the interview!

A specialized model used by researchers is becoming a valuable tool for studying human brain development, diseases and potential treatments, according to a team of scientists at Rutgers University-New ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

In this whitepaper, Sartorius discusses the need to replace animal testing with advanced in vitro human cell models for pharmaceutical, chemical, and cosmetic development as, with only 5-10% of ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions ...