The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...

Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and ...

Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain. A protein from Helicobacter pylori inhibits amyloid formation in both ...

Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and ...

Balanced synaptic inhibition, controlled by multiple synaptic adhesion proteins, is critical for proper brain function. MDGA1 (meprin, A-5 protein, and receptor protein-tyrosine phosphatase mu [MAM] ...

This is a preview. Log in through your library . Abstract Cleavage and release of membrane protein ectodomains, a regulated process that affects many cell surface proteins, remains largely ...

(A, B) ALP staining and activity detection were performed after treating cells with APPswe or BMP2 for 5 days or 7 days. (C, D) ARS staining and semiquantitative analysis were used to detect calcium ...

Alzheimer's disease often begins many years before memory problems appear. During that silent phase, toxic changes slowly build inside the brain. For decades, scientists focused mostly on amyloid ...