DNA methylation, a key epigenetic alteration, has been implicated in the tumorigenesis of various cancers; however, its diagnostic value through circulating tumor DNA (ctDNA) remains unrealized in ...

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array ...

DNA methylation is a widely studied epigenetic modification with crucial roles in gene regulation, development, and disease, particularly in cancer. It has immense potential as a biomarker for early ...

The race for early cancer detection is one that physicians have been running for millennia. In one of humanity’s oldest surviving medical texts, the ancient Egyptian physician Imhotep described 46 ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

A recent eBioMedicine study explores the association between air pollution and colorectal cancer (CRC) risk based on epigenomic analysis. Study: Impact of ambient air pollution on colorectal cancer ...

Chronic diseases such as cardiovascular disease, cancer, and diabetes are driven by systemic inflammation, a natural biological response to harmful stimuli, injuries, or infections. C-reactive protein ...