Researchers are shifting focus from large arteries to microvessels, where nitric oxide activity may signal early circulatory ...

Transient receptor potential canonical channels are essential for maintaining the function of human pulmonary endothelial cells in PAH.

Empagliflozin reduced proinflammatory cytokines and oxidative stress markers in INOCA patients with CMD, improving vascular health. Treatment led to favorable shifts in endothelial extracellular ...

On November 2, 2025, the research group led by Dr. Zeng Ling from Army Medical University systematically elucidated the molecular mechanisms, ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

Preclinical data suggest neratinib dampens vascular inflammation and atherosclerosis by targeting ASK1 in endothelial cells, ...

Microvascular endothelial dysfunction is an early or inductive event that occurs in the development of cardiovascular diseases and associated organ damage. The endothelium is composed of a single ...

Microvascular endothelial dysfunction (MiVED) is implicated in several health conditions, such as hypertension, atherosclerotic cardiovascular disease ...

These changes contribute to microvascular dysfunction through mechanisms such as endothelial dysfunction, impaired nitric oxide availability, inflammation, and oxidative damage. Understanding this ...