Using artificial intelligence, researchers show how γ-secretase recognizes substrates – an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Usually enzyme complexes make multistep processes easier by catalyzing sequential reactions in which the product of one enzyme becomes the substrate for the next. In a new finding, researchers report ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was ...

Researchers have identified an enzyme that can assemble into complexes with fractal geometries. Fractals—hierarchical patterns in which structural features at larger scales repeat at smaller ...

Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. The research, ...

Alzheimer’s disease is likely caused by stalled protein processing in the brain, according to a new study. The research, published today as a Reviewed Preprint in eLife, is described by editors as a ...