Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug ...

A fast-aging fish is giving scientists a rare, accelerated look at how kidneys grow old—and how a common drug may slow that process down. Researchers found that SGLT2 inhibitors, widely used to treat ...

Objective Macrophages and kidney cell pyroptosis/ferroptosis could play an important role in the pathogenesis of lupus ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood. It is a common health concern that affects an estimated 8–16% ...

This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...

CCL5 protects podocytes, the kidney’s essential filtration cells, but simultaneously drives harmful inflammation. Ultimately, these damaging effects surpass its protective role, leading to progressive ...