Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

Chinese Medical Journals Publishing House Co., Ltd. The small intestine is not only essential for digestion and nutrient absorption but also for immune regulation and maintaining a balanced microbial ...

The farnesoid X receptor (FXR), a bile acid receptor, plays a direct role regulating innate immune cells in the gut, and treating mice with an FXR agonist improved symptoms of inflammatory bowel ...

Researchers have used a mouse model to show that infections in the intestine can change the composition of bile, a fluid that is generated in the liver and is crucial to digestion. Bile aids in the ...

The human gut is home to trillions of microbes that not only aid in digestion but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range of ...

If the COVID-19 pandemic has done one thing, it’s made us all more familiar with some of the important players in the immune system. Antibodies, B cells, and T cells are among the best known parts of ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Immuno-oncology is an evolving field of study on the role of the immune system in cancer initiation and growth. This introductory module describes the purpose of the human immune system, components of ...