This is a preview. Log in through your library . Abstract The classification of MAP 2 as a microtubule-associated protein is based on its affinity for microtubules in vitro and its filamentous ...

Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...

Cells exist in three dimensions, and they have a dynamic skeleton and filaments that help them maintain and stabilize their form and structure. The molecules that create the cellular cytoskeleton, ...

In this report I describe a new protein, defined by a monoclonal antibody, which is associated with vimentin filaments in a variety of cultured cells and in skeletal muscle. By immunofluorescence it ...

Structures called desmosomes connect cells to each other and transfer mechanical stress. They are especially important in tissues under continual mechanical stress, such as heart muscle (pictured).

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

Most biological cells have a fixed place in an organism. However, cells can become mobile and move through the body. This happens, for example, during wound healing or when tumor cells divide ...

How did life leap from simple microbial cells to the complex, structured cells that make up animals, plants, and fungi? A new study in The EMBO Journal by researchers at the Indian Institute of ...