A new kinase joins the ranks of those linking a miscreant cell cycle to Alzheimer disease (AD). A June 12 article in press in Neurobiology of Disease shows that PCTAIRE 3, a homolog of Cdc2 kinases, ...
Lipid kinases are among the promising targets of new classes of drugs, due mainly to class I PI3Kα, which plays a crucial role in carcinogenesis and metastasis. This enzyme is hyperactive in 30-40% of ...
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