In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

Muscles are formed by the merging of many small myoblasts into larger myofibers. This fusion of mononucleated myoblasts with a single nucleus into multinucleated myofibers with multiple nuclei is an ...

Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...

Skeletal muscle and cardiovascular diseases continue to pose significant challenges to public health, affecting a wide range ...

Scientists obtained stem cells expressing cardiac muscle-specific genes and proteins. The cells displayed regular rhythmic contractions similar to a heart, confirming that they were functional ...