Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...

If the cellular machinery skips the first start codon and detects a second one, it may build a shorter version of the protein. In other cases, the machinery may detect a section that closely resembles ...

Methane-producing archaea from the species Methanosarcina acetivorans. The microbes are stained with a fluorescent dye that specifically binds to the membranes of archaea. The beauty of the DNA code ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...