Purpose: Mitochondrial DNA testing is typically performed by targeted mutation analysis only. We applied a more comprehensive approach to study the mitochondrial genome in 24 pediatric patients with ...

Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer Low-pass whole-genome and targeted ...

Scientists describe a new method for detecting point mutations. The technique can be applied in living cells, offering a rapid, highly accurate and inexpensive means of identifying mutations relevant ...

Single nucleotide polymorphisms (SNPs) and circulating endothelial cells (CECs) as outcome predictors in patients (pts) with recurrent glioblastoma (rGBM) treated with bevacizumab (BEV) and sorafenib ...

There is little doubt within the scientific community of the immense impact that next-generation sequencing (NGS) has had on translational research. Techniques like liquid biopsy have allowed ...

Expands Biocept's intellectual property globally for methods of detecting rare mutations, including cancer biomarkers associated with circulating tumor DNA (ctDNA) SAN DIEGO, April 2, 2020 /PRNewswire ...

Using data to identify the genetic changes that cause healthy cells to become malignant can help doctors select therapies that specifically target the tumor. Most of the roughly 40 trillion cells of ...

Against this backdrop, a team led by Professor Zhang Han and Associate Professor Chen Zhi from Shenzhen University in China , has demonstrated an innovative approach that combines DNA origami, CRISPR ...

Researchers have discovered that the human body’s 3 trillion cells aren’t clones of a single DNA sequence, as is widely believed. Instead, the cells of the human body contain a plethora of altered DNA ...

In a recent study posted to the medRxiv* preprint server, researchers analyzed the primer and probe sequences of the United States Centers for Disease Control and Prevention (CDC) recommended ...