Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Sickle cell disease (SCD) is a group of hereditary red blood cell disorders. Sickle cell anemia is a type of SCD that occurs when a person inherits genes containing an atypical form of hemoglobin.

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Why do alterations of certain genes cause cancer only in specific organs of the human body? Scientists have now demonstrated that cells originating from different organs are differentially susceptible ...

The neurodevelomental disease Rett syndrome is usually caused by mutations in a gene called MECP2, which is located on the X chromosome. Patients lose coordination, mobility, and their ability to ...

The Food and Drug Administration has approved a new cancer drug that is the first to be designed from the start to fight a specific genetic mutation, not a traditional cancer type. The new drug, named ...

Women with mutations in the BRCA1 or BRCA2 genes are well known to have an increased risk of developing both breast and ovarian cancer. As well as this, links have also been shown to both breast and ...