Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...
In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...
Magdalena (Magda) Zernicka-Goetz, today a developmental and stem cell biologist at the University of Cambridge and California Institute of Technology, recalled being an artistic child who enjoyed ...
Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found ...
Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...
Neural crest cells are a population of stem cells that invade the embryo in early development. They play a big role in what ...
A new study from the MRC Laboratory of Medical Sciences (LMS) in London, UK reveals how ancient viral DNA once written off as "junk" plays a crucial role in the earliest moments of life. The research, ...
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