Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a ...

Different DNA Structures Nucleate the Folding of Proteins to form specific complexes that modulate the readout of ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 ...

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

Artificial intelligence isn’t just changing how we search the web or generate images. It is reshaping how scientists approach one of biology’s oldest problems: the folding of proteins. Google DeepMind ...

In recent years, the integration of computational and machine learning techniques has dramatically advanced our understanding of protein function and engineering. As proteins underpin virtually every ...

Proteins play a critical role in cellular function by interacting with other biomolecules; missense variants that cause loss of protein function can lead to a broad spectrum of genetic disorders.

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...