In this analysis of patients with myeloperoxidase-ANCA-positive AAV, all urinary complement C3 fragment levels were elevated significantly compared with healthy controls (P .01 for all). Specific ...
Complement 3 glomerulopathy (C3G) is considered a very rare disease. With C3G, patients have issues with their immune system that cause kidney damage and symptoms such as swelling and changes in urine ...
Please provide your email address to receive an email when new articles are posted on . Pegcetacoplan reduced proteinuria in patients with rare complement-mediated glomerular diseases vs. placebo.
Acute chest syndrome (ACS), a life-threatening complication of sickle cell disease (SCD), may be driven by overactivation of the complement system, according to new research. The study suggests that ...
Q: What did this study reveal about sleep and health? A: An analysis of sleep data from over 88,000 people found that poor sleep patterns—especially irregular bedtimes and unstable circadian ...
Kawasaki Disease (KD) is an acute febrile systemic vasculitis of unknown etiology and the leading cause of acquired heart disease among children. The complement system is a major component of innate ...
A single treatment with a CRISPR-Cas9 based gene editing therapy is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful ...
Complement activation in patients with AAV who are in remission may be reflective of ongoing renal scarring. Persistent complement activation during disease remission in antineutrophil cytoplasmic ...
Malaria remains one of the most devastating diseases worldwide. Blocking malaria transmission is considered a promising strategy for controlling and potentially eliminating the disease. In this study, ...
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