Objective: To quantitatively examine immune cell markers and spatial distribution in human diabetic kidney disease (DKD) to enhance understanding of the inflammatory landscape contributing to injury.

NanoString Technologies, Inc. (NASDAQ:NSTG), a leading provider of life science tools for discovery and translational research, today announced the publication of a new peer-reviewed study utilizing ...

Integrating NGS with single-cell and spatial platforms has redefined modern multiomic research. Next-generation sequencing (NGS) has become the backbone of modern biological research, but its highest ...

Yabaji et al. reports a fundamental study highlighting the mechanistic connection for susceptibility to TB infection via the sst1 locus, this was shown to involve increased IFN and Myc production ...

GeoMx-DSP Spatial Transcriptomics data for "Tumor-derived Lactate Imposes a Metabolic Barrier to B Cell Infiltration and TLS Formation" FFPE TNBC tumor tissue sections were processed for spatial ...

Patients with stage III clear cell renal cell carcinoma are at high risk for recurrence after nephrectomy. To mitigate overtreatment, there is a pressing clinical need to determine which patients ...

Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT ...

bCenter for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA cDepartment of Pediatrics and the Herman B Wells Center for Pediatric Research, Indiana ...

A seminal decision concerning second medical use patents and questions over confidentiality were among the top talking points this fortnight This edition of our Unified Patent Court update covers a ...

Intravesical Bacillus Calmette-Guérin (BCG) immunotherapy is the gold standard for high-risk NMIBC, however over half of patients experience early recurrence or disease progression, highlighting the ...