Diabetic retinopathy develops through complex microvascular damage driven by chronic hyperglycemia, yet traditional risk factors such as disease duration or glycemic control explain only part of ...

Diabetic retinopathy develops through complex microvascular damage driven by chronic hyperglycemia, yet traditional risk factors such as disease duration or glycemic control explain only part of ...

US scientists have reported that restoring tryptophan metabolism in the gut microbiome can help to protect patients with diabetes from vision loss ...

Links between gut dysfunction and the eye may reveal therapeutic strategies for individuals with diabetic retinopathy ...

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are incompletely understood. Objective We used strategies to increase either ...

Choroidal dysfunction plays a crucial role in retinal diseases, highlighting its potential as a therapeutic target and the need for innovative treatments. Increasingly, the choroid is being recognized ...

Diabetic retinopathy and its effect on retinal sensitivity should be considered in the design of interventional trials for capillary nonperfusion. Retinal capillary nonperfusion (CNP) is linked with ...

chromatic sensitivity changes in normal and glucose-dysfunctional states. The study included 18 participants (mean age, 49.4 years), 9 control individuals (HbA1c ≤5.6%) and 9 individuals with glucose ...

FALCON study involved 47 patients with ADOA across the US, UK, Italy, and Denmark, assessing disease progression over 24 months. Results showed slow progression of OPA1-associated ADOA, with 24% ...

Contributed by Douglas C. Wallace; received April 4, 2025; accepted August 13, 2025; reviewed by Yair Anikster, Paolo Bernardi, Fernando Scaglia, and A. Phillip West Herein, we describe the creation ...

≤5.6%) and 9 individuals with glucose dysfunction (HbA1c ≥5.7%) with no or mild retinopathy. …this study demonstrated that the novel color perimeter is highly repeatable and has the potential to ...