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  1. PTPRC - Wikipedia

    PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally called leukocyte common antigen (LCA). [6] PTPRC is a critical enzyme involved in …

  2. CD45 Marker and Its Role in Immune Cell Regulation

    Apr 29, 2025 · CD45 is a crucial protein on most immune cells, functioning as a phosphatase that regulates signaling pathways controlling immune responses. Its widespread expression and …

  3. Pathology Outlines - CD45 (LCA)

    Feb 1, 2022 · CD45 is a ubiquitous cell surface marker of nucleated hematopoietic cells involved in the regulation and activation of the immune system

  4. CD45 in human physiology and clinical medicine - PubMed

    CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of the hematopoietic system. It is characterized by the …

  5. What is CD45? - MyPathologyReport

    CD45 is a protein found on the surface of most cells in the immune system, including white blood cells (also called leukocytes). CD45 helps these immune cells communicate and respond …

  6. What Are CD45 Positive Cells and Why Do They Matter?

    Nov 16, 2025 · CD45 positive cells carry the Cluster of Differentiation 45 (CD45) protein marker on their surface. This surface marker serves as a universal identification tag for almost every …

  7. CD45 in human physiology and clinical medicine - ScienceDirect

    Apr 1, 2018 · CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of the hematopoietic system. It is characterized by …

  8. What Are CD45 Cells and What Is Their Function?

    Jul 23, 2025 · CD45 is a protein found on the surface of nearly all white blood cells, also known as leukocytes. This protein acts as a distinguishing marker, helping to identify these immune cells …

  9. Differential Regulation of CD45 Expression on Granulocytes, …

    CD45 (common leucocyte antigen) is a transmembrane glycoprotein with a molecular weight of 180–220 kDa expressed on all leucocytes and constitutes about 10% of cell surface antigens …

  10. Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

    The leucocyte common antigen, protein tyrosine phosphatase receptor type C (PTPRC), also known as CD45, is a transmembrane glycoprotein, expressed on almost all haematopoietic …