
How Cancer Tumors Hijack the Body’s Defense System
May 10, 2024 · Authors note that tumors likely employ a variety of strategies to evade immune detection. But the discovery could lead to a new approach for targeted cancer therapies.
Unlocking NK cells: Novel checkpoint targets revolutionize cancer ...
Aug 5, 2025 · A comprehensive analysis published in Reserch illuminates how cancer cells hijack immune checkpoints on natural killer (NK) cells to disable the body’s frontline defense system.
Frontiers | Targeting immune checkpoints on tumor-associated ...
May 29, 2023 · Tumor-associated macrophages (TAMs) are the predominant immune cells that infiltrate the tumor microenvironment and express a variety of immune checkpoints that impact immune …
CD300a: An Innate Immune Checkpoint Shaping Tumor Immunity …
May 27, 2025 · Recent studies suggest that tumor cells may hijack CD300a-associated pathways to establish an immunosuppressive microenvironment that facilitates immune evasion, tumor survival, …
The present study was initiated by comparing publicly available transcription profiles of tumor tissues from responsive and resistant ICB-treated patients across various cancer types.
How Cancer ‘Hijacks’ Your Immune System And What You Can Do …
Feb 4, 2025 · A new study from the Chiba Cancer Center in Japan has revealed that cancer cells can hijack your immune system’s T-cells, stealing their energy and making them ineffective.
Immune checkpoints in the tumor microenvironment
Oct 1, 2020 · Interactions between immune checkpoints (ICs) and their ligands negatively regulate T cell activation pathways involved in physiological immune respon…
The Role of Immune Checkpoint Inhibitors in Cancer Therapy
Mar 13, 2025 · However, tumor cells have developed sophisticated ways to evade detection, including hijacking the immune system’s brake mechanism, known as immune checkpoints.
Immune checkpoint blockade in cancer: current insights and future ...
Jan 2, 2026 · The advent of immune checkpoint inhibitors has yielded durable clinical responses in diverse malignancies, substantiating their role as foundational agents in cancer therapy. …
Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune system. It essentially hacks the immune cells, transferring its...